The Ghana College of Physicians and Surgeons is a public institution that was established in 2003 to provide post-graduate medical training in medicine, surgery and related disciplines.

Several factors influenced the establishment of the College including:

• frustration on the part of the government on the returns on investment put in the West African Postgraduate Medical College.
• high attrition rate of medical practitioners given sponsorship for postgraduate professional training abroad.
• a strong desire to stem the brain-drain by establishing a local national postgraduate training institution.

The efforts of Ministers for Health, Health professionals and the Ghana Medical Association accumulated in the

setting up of a Task Force chaired by Professor George W. Brobby to make recommendations for the establishment of the National Postgraduate Medical College in 2000.

In 2001, Professor Paul K. Nyame was appointed the Acting-Rector of the Ghana College of Physicians and Surgeons with the responsibility of establishing a Secretariat for the College.

On 9th December 2003, the College was inaugurated by President J A Kufuor with Professor Samuel Ofosu-Amaah as the first President and Chairman of Council, Professor Paul K. Nyame as the Rector and Prof George W. Brobby as Vice-Rector.

The first group of Residents was enrolled into the College in September 2004 and graduated in September 2007. They were inducted into Membership of Ghana College of Physicians and Surgeons in December 2007.